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ey0015.2-13 | Primary cells isolated from the umbilical cord of offspring born to mothers with GDM maintain metabolic and molecular imprints of maternal hyperglycemia | ESPEYB15

Primary cells isolated from the umbilical cord of offspring born to mothers with GDM maintain metabolic and molecular imprints of maternal hyperglycemia

AI Amrithraj , A Kodali , L Nguyen , AKK Teo , CW Chang , N Karnani , KL Ng , PD Gluckman , YS Chong , W Stünkel

To read the full abstract: Endocrinology. 2017 Jul 1;158(7):2102-2112Gestational diabetes mellitus (GDM) produces fetal hyperglycemia with increased lifelong risks for the exposed offspring to cardiovascular and other diseases. In-utero exposure to GDM alters metabolic programming in newborns and their placenta, cord tissues, and cord blood. Human umbilical cord mesenchymal stromal cells (hUC-MSCs...

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ey0020.12-12 | Food for Thought | ESPEYB20

12.12. Associations between infant screen use, electroencephalography markers, and cognitive outcomes

EC Law , MX Han , Z Lai , S Lim , ZY Ong , V Ng , LJ Gabard-Durnam , CL Wilkinson , AR Levin , A Rifkin-Graboi , LM Daniel , PD Gluckman , YS Chong , MJ Meaney , CA Nelson

Brief summary: In the prospective population-based Growing Up in Singapore Toward Healthy Outcomes (GUSTO) study (n=437 children, 51.9% boys), the effect of parent-reported screen time in infancy was tested on EEG characteristics and correlated to cognitive outcome. Mean daily screen time at 12 months of age was 2 hours. Infant screen time was associated with altered cortical EEG activity at 18 months and was suggested to explain observed alterations in attention and ...

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ESPE Yearbook of Paediatric Endocrinology

Primary cells isolated from the umbilical cord of offspring born to mothers with GDM maintain metabolic and molecular imprints of maternal hyperglycemia

12.12. Associations between infant screen use, electroencephalography markers, and cognitive outcomes

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